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Once upon a time, a “wellness holiday” meant spa water, soft robes, and a Swedish massage before dinner. Now, the most coveted escapes promise something rarer: repair. Today’s ultra-luxe resorts are pairing serious medicine (think genomics, epigenetic testing, HRV and sleep mapping, continuous glucose monitoring, even VO₂ max and DEXA) with couture-level hospitality. If you’re looking to switch off while quietly turning back a dial or two, here are the places you need to bookmark.
A Swiss icon on Lake Geneva, CLP has treated A-list royals, artists, and CEOs since 1931. Its storied Revitalisation programme made cellular therapy glamorous; today, the clinic combines old-world discretion with cutting-edge diagnostics and menus plated like Michelin art. Days move between physician consults, vascular and metabolic screening, IV micronutrients, and alpine light—this is, after all, precision medicine wrapped in silk.
Revitalisation and Master Detox pathways; epigenetic and inflammatory profiling; IV nutrient therapy; sleep and stress mapping; advanced aesthetic medicine with medical oversight.
Starts from CHF 20,000–40,000 (Rs 2234124 to 4468248 approximately) per week; many signature pathways are priced on request.
Led by Dr Mark Hyman, who has dedicated 30 years to creating health and preserving life, RoseBar’s Longevity Club promises to defy the concept of ageing. The retreat uses in-depth diagnostic testing to create a customised programme that provides the knowledge and tools you need for a healthy and long life.
RoseBar folds functional medicine into bohemian glamour: think sunrise breathwork on the bay, biological-age testing, peptides, mitochondrial-minded nutrition, cold/heat cycles, and movement coaching. And while the days are treatment-led, the nights are candlelit—this is Ibiza, after all.
The RoseBar Signature Longevity Program, Dr Mark Hyman Young Forever Detox Program
Programmes typically start from €2,500 (Rs 2,57,405 approximately) for 3 days.
An integrative wellness clinic, AEON aims to maintain the integrity and efficiency of the cell, especially for those over the age of 35. It achieves this by turbocharging your energy powerhouses (mitochondria), repairing damaged cellular blueprints (DNA), calming internal inflammation, and teaching your body how to manage stress at the deepest level. The clinic majors in advanced testing—genomics, endocrine, cardiometabolic—layered with IVs, peptides (as indicated), hyperbaric sessions, and performance coaching.
Full-stack diagnostics; CGM; HBOT; IV nutrient and NAD+ protocols; hormone optimisation programmes.
Membership and programme prices are available on request.
Calling itself ‘the world’s best longevity clinic’, Lanserhof integrates state-of-the-art medical science with proven alternative healing approaches. The Lanser Method is gut rest, metabolism repair, and immaculate silence. Treatments feature an intelligent mix of naturopathy, energy medicine, psychology, psychoneuroimmunology, chronomedicine, and modern top-tier medicine. Rooms are monastery-chic and plates are clinically clean yet delicious.
DEXA; CPET (VO₂ max); respiratory muscle training; microbiome- and metabolism-focused nutrition; osteopathy and fascia therapy.
From €5,900 per week (programme + board).
Mediterranean sunlight meets medical polish at SHA Wellness Clinic. Featuring 50+ integrative medical and wellness specialties, SHA is currently operational in two destinations, with a third one (UAE) opening in 2027. The retreat layers sleep clinics, cognitive and stress testing, functional medicine, and aesthetic dermatology with macro-Mediterranean cuisine. Its Advanced Longevity Program promises to optimise your health by delaying or reducing the effects of ageing.
Sleep lab; neuro-cognitive and stress testing; metabolic and weight-management tracks; advanced aesthetic medicine.
From €7,500 (Rs 7,71,502) for the 7-day Advanced Longevity Program (not inclusive of stay).
The most glamorous address in Phuket now has serious clinical muscle: physician-led assessments, IVs where appropriate, breath and heat/cold stacks, strength and mobility coaching. The Amanpuri Holistic Wellness Centre offers a full range of integrated medical services with access to doctors, nurses, physiotherapists, and even Traditional Chinese Medicine practitioners.
Metabolic and hormonal panels; IV nutrient therapy; breathwork; red-light/cryo; musculoskeletal re-education.
Programmes typically from US$7,000–$12,000 (Rs 620791 to 1064213) per 5–7 days; villas separate.
A Himalayan classic with deep Ayurvedic roots and modern diagnostics, Ananda’s programmes start with dosha-led consults and expand into metabolic/hormonal labs, posture and mobility analysis, TCM touches and physiotherapy. Each wellness programme is monitored through specific parameters that align with the guest’s health objectives. Common metrics include weight tracking, sleep quality assessment, stress monitoring, postural and gait analysis by physiotherapists, and continuous blood glucose monitoring. You depart with a 12-week plan and recipes, not platitudes.
Weight & metabolic health; stress-sleep repair; women’s health & fertility; Panchakarma; detox; stress management.
From approximately Rs 6–10 lakh for 14–21 nights (programme + board).
At Vana, “longevity” isn’t an add-on—it’s the operating system. The retreat layers Ayurveda, Yoga, and Sowa Rigpa with modern screenings (Ayurgenomics, wellness checks, HRV, InBody) in a pace that feels unhurried and deeply humane: restoration before optimisation, rhythm over rush. Your day moves from morning light, movement, and nature to evenings of soft lighting, sleep-focused meals, breathwork, and calming therapies like Shirodhara or sound healing—supported, if useful, by measures that actually matter (sleep efficiency, HRV, metabolic markers), not just spa-day sentiment. Crucially, there are no IVs here; Vana favours governance, sequencing, and safety over theatrics.
Sleep, detox, Tibetan healing, and stress-resilience pathways; pulse diagnosis; InBody/HRV; breath and contemplative practices.
From Rs 55,000 per night, including wellness board, consultations, group sessions, and baseline assessments; add-ons vary by goal and program intensity.